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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gria2tm1Rlh
targeted mutation 1, Richard L Huganir
MGI:3584143
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gria2tm1Rlh/Gria2tm1Rlh involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3589567


Genotype
MGI:3589567
hm1
Allelic
Composition		 Gria2tm1Rlh/Gria2tm1Rlh
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria2tm1Rlh mutation (1 available); any Gria2 mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
impaired synaptic plasticity ( J:99813 )
• following high-frequency stimulation on the cerebellum slice culture, no increase in the rectification ratio was observed, indicating that calcium-permeable AMPA receptor plasticity (CARP) does not occur in these mutant mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory