Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rcvrntm1Clma mutation
(1 available);
any
Rcvrn mutation
(15 available)
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vision/eye
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• visual threshold, the light intensity at which the time to find a platform was 50% of that in darkness, is about 4-fold higher than in controls
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• shorter integration time of dim flash responses in ganglion cells, rod cells and rod bipolar cells, resulting in a quicker return to baseline
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rcvrntm1Clma mutation
(1 available);
any
Rcvrn mutation
(15 available)
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vision/eye
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• faster flash response recovery in dark-adapted rods
• phosphodiesterase adaptation is absent in rods
• calcium dynamics are accelerated in rods in response to bright, saturating flashes of light
• electroretinograms exhibit two corneal positive b-waves rather than one in response to a single midrange scotopic flash
• sensitivity of rods to steps of lights is decreased
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Guca1a/Guca1btm1Jnc mutation
(0 available);
any
Guca1a mutation
(11 available)
Rcvrntm1Clma mutation
(1 available);
any
Rcvrn mutation
(15 available)
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vision/eye
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• reduction in the single photon response amplitude and a corresponding increase in the half-saturating flash strength, and shortened time-to-peak and integration time of the dim flash response when compared to homozygous Guca1a/Guca1btm1Jnc mutant mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Guca1a/Guca1btm1Jnc mutation
(0 available);
any
Guca1b mutation
(9 available)
Rcvrntm1Clma mutation
(1 available);
any
Rcvrn mutation
(15 available)
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vision/eye
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• reduction in the single photon response amplitude and a corresponding increase in the half-saturating flash strength, and shortened time-to-peak and integration time of the dim flash response when compared to homozygous Guca1a/Guca1btm1Jnc mutant mice
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