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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gata1tm8.1Sho
targeted mutation 8.1, Stuart H Orkin
MGI:3582685
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gata1tm8.1Sho/Gata1tm8.1Sho involves: 129S1/Sv * C57BL/6 MGI:3582840
ot2
 		Gata1tm8.1Sho/Y involves: 129S1/Sv * C57BL/6 MGI:3582859


Genotype
MGI:3582840
hm1
Allelic
Composition		 Gata1tm8.1Sho/Gata1tm8.1Sho
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm8.1Sho mutation (0 available); any Gata1 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal megakaryocyte morphology ( J:99310 )
• transient (E9.5-E11.5) hyperproliferative yolk sac megakaryocyte colony-forming units observed by colony assay




Genotype
MGI:3582859
ot2
Allelic
Composition		 Gata1tm8.1Sho/Y
Genetic
Background		 involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm8.1Sho mutation (0 available); any Gata1 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal megakaryocyte morphology ( J:99310 )
• transient (E9.5-E11.5) hyperproliferative yolk sac megakaryocyte colony-forming units observed by colony assay




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory