All Phenotypes Ero1b<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ero1b⁺
wild type
MGI:3581716

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ero1b^{Gt(P077G11)Wrst}/Ero1b⁺	involves: 129S2/SvPas * C57BL/6	MGI:4441479
cx2	Ero1b^{Gt(P077G11)Wrst}/Ero1b⁺ Ins2^Akita/Ins2⁺	involves: 129S2/SvPas * C57BL/6NSlc	MGI:4441480

Allelic Composition	Ero1b^{Gt(P077G11)Wrst}/Ero1b⁺
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ero1b^{Gt(P077G11)Wrst} mutation (0 available); any Ero1b mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal glucose homeostasis ( J:158805 )

• mice exhibit an elevation in the glucose to insulin ratio compared with wild-type mice

decreased insulin secretion ( J:158805 )

• in the pancreas

increased circulating glucose level ( J:158805 )

impaired glucose tolerance ( J:158805 )

endocrine/exocrine glands

decreased insulin secretion ( J:158805 )

• in the pancreas

Allelic Composition	Ero1b^{Gt(P077G11)Wrst}/Ero1b⁺ Ins2^Akita/Ins2⁺
Genetic Background	involves: 129S2/SvPas * C57BL/6NSlc

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ero1b^{Gt(P077G11)Wrst} mutation (0 available); any Ero1b mutation (32 available)
Ins2^Akita mutation (14 available); any Ins2 mutation (90 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased insulin secretion ( J:158805 )

• in the pancreas

increased circulating glucose level ( J:158805 )

• plasma glucose levels are higher than in Ins2^Akita heterozygotes

impaired glucose tolerance ( J:158805 )

• glucose intolerance is worse than in Ins2^Akita heterozygotes

endocrine/exocrine glands

small pancreatic islets ( J:158805 )

decreased insulin secretion ( J:158805 )

• in the pancreas

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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