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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hrastm1Grnt
targeted mutation 1, Seth G N Grant
MGI:3580632
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hrastm1Grnt/Hrastm1Grnt involves: 129P2/OlaHsd MGI:3581303
cx2
 		Hrastm1Grnt/Hrastm1Grnt
Syngap1tm1Grnt/Syngap1+ 		involves: 129P2/OlaHsd * MF1 MGI:3581305


Genotype
MGI:3581303
hm1
Allelic
Composition		 Hrastm1Grnt/Hrastm1Grnt
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Grnt mutation (0 available); any Hras mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:98903 )
N
• 150 pulse trains of 5 Hz synaptic stimulation induced similar amounts of long term potentiation in the hippocampal CA1 region as in wildtype




Genotype
MGI:3581305
cx2
Allelic
Composition		 Hrastm1Grnt/Hrastm1Grnt
Syngap1tm1Grnt/Syngap1+
Genetic
Background		 involves: 129P2/OlaHsd * MF1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrastm1Grnt mutation (0 available); any Hras mutation (30 available)
Syngap1tm1Grnt mutation (0 available); any Syngap1 mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:98903 )
• long term potentiation induced by 150 pulses of 5 Hz stimulation in the hippocampal CA1 region was reduced compared to wildtype and single homozygous Hras1 mutants




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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory