All Phenotypes Axin1<tm2Cos> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Axin1^tm2Cos
targeted mutation 2, Frank Costantini
MGI:3580423

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Axin1^tm2Cos/Axin1^tm2Cos	involves: 129S6/SvEvTac * FVB/N	MGI:3582068

Allelic Composition	Axin1^tm2Cos/Axin1^tm2Cos
Genetic Background	involves: 129S6/SvEvTac * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Axin1^tm2Cos mutation (0 available); any Axin1 mutation (44 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:98893 )

• mice homozygous for a null mutation were fertile and had normal life span; no premature deaths, obvious behavioral defects or overt tumors were found

• difference of 11 to 14 % less in weight compared to wild-type control at birth to 28 days is observed; this difference was only 5 to 6% and was not statistically significant by 6 weeks

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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