Analysis Tools
vision/eye
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• electroretinograms (ERGs) of dark-adapted 12 week old mutant mice lack the rod b-wave and scotopic threshold response (STR), although the cone electroretinograms are of high amplitude
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Allele Symbol Allele Name Allele ID |
Grm6nob4 no b wave 4 MGI:3580353 |
| Summary |
3 genotypes |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• electroretinograms (ERGs) of dark-adapted 12 week old mutant mice lack the rod b-wave and scotopic threshold response (STR), although the cone electroretinograms are of high amplitude
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• ON retinal ganglion cell responses are delayed compared to in wild-type mice
• the spatial frequency cutoffs are lower than in wild-type mice
• however, peak contrast sensitivity is normal
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• photopic b-waves are absent
• however, a-waves are normal
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• scotopic b-waves are absent
• mice lack a scotopic threshold response unlike wild-type mice
• however, a-waves are normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• spatial frequency threshold is lower than in wild-type mice
• the spatial frequency cutoffs are lower than in wild-type mice
• however, peak contrast sensitivity is normal
|
|
• photopic b-waves are absent
• however, a-waves are normal
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• scotopic b-waves are absent
• mice lack a scotopic threshold response unlike wild-type mice
• however, a-waves are normal
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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