Analysis Tools
immune system
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• spleen architecture is largely restored compared to Lta-deficient mice; extensive networks of T zone stromal cells are observed
• splenic dendritic cell numbers are restored
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• although T zone stromal areas are extensive compared to Lta-deficient mice, distribution of gp38+ staining differs from wild-type with a higher concentration of positive cells near the boundary of the B and T zones
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• transgene expression does not restore lymph node or Peyer's patch development in Lta-deficient mice
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hematopoietic system
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• although T zone stromal areas are extensive compared to Lta-deficient mice, distribution of gp38+ staining differs from wild-type with a higher concentration of positive cells near the boundary of the B and T zones
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