All Phenotypes Acan<tm1Afos> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Acan^tm1Afos
targeted mutation 1, Amanda J Fosang
MGI:3577026

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Acan^tm1Afos/Acan^tm1Afos	involves: C57BL/6	MGI:3577366

Allelic Composition	Acan^tm1Afos/Acan^tm1Afos
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acan^tm1Afos mutation (1 available); any Acan mutation (80 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:97622 )

• mutants develop normally with no skeletal abnormalities but do not accumulate aggregan in cartilage even though Agc1 is not cleaved by matrix metalloproteases

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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