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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		hlb258
heart, lung and blood 258
MGI:3575167
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		hlb258/? involves: 129S4/SvJae * C57BL/6J MGI:3575261


Genotype
MGI:3575261
ot1
Allelic
Composition		 hlb258/?
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
hlb258 mutation (1 available); any hlb258 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased circulating fibrinogen level ( J:82961 )
• low fibrinogen; at 6 weeks of age, this mouse had a plasma fibrinogen level of 67.4

homeostasis/metabolism
decreased circulating fibrinogen level ( J:82961 )
• low fibrinogen; at 6 weeks of age, this mouse had a plasma fibrinogen level of 67.4
abnormal blood coagulation ( J:82961 )
• described as coagulopathy




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory