Phenotypes associated with this allele

• Allele Symbol: Qki^qk-2J
• Allele Name: quaking 2 Jackson
• Allele ID: MGI:3575120
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Qki^qk-2J/Qki^qk-2J	B6.Cg-Qki^qk-2J/GrsrJ	MGI:3639278
ht2	Qki^qk-2J/Qki^qk-shk	involves: 129 * C57BL/6 * C57BLKS/J	MGI:5637522

Genotype
MGI:3639278

hm1

• Allelic Composition: Qki^qk-2J/Qki^qk-2J
• Genetic Background: B6.Cg-Qki^qk-2J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Abnormal myelin sheath morphology of Qki^qk-2J/Qki^qk-2J spinal cord (right) compared to control (left)

mortality/aging

postnatal lethality, incomplete penetrance ( J:97293 )

• variable survival with some homozygotes living to adulthood

nervous system

abnormal striatum morphology ( J:97293 )

• holes are found in the striatum of the cortex and cerebellum

abnormal myelin sheath morphology ( J:97293 )

• holes are found in the myelin of the spinal cord

behavior/neurological

tremors ( J:97293 )

• rapid tremors visible by 2 weeks of age most apparent during locomotion

Genotype
MGI:5637522

ht2

• Allelic Composition: Qki^qk-2J/Qki^qk-shk
• Genetic Background: involves: 129 * C57BL/6 * C57BLKS/J

behavior/neurological

tremors ( J:220956 )