All Phenotypes nmf313 MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

nmf313
neuroscience mutagenesis facility, 313
MGI:3531433

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	nmf313/nmf313	C57BL/6J-nmf313/J	MGI:3574835

Allelic Composition	nmf313/nmf313
Genetic Background	C57BL/6J-nmf313/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
nmf313 mutation (1 available); any nmf313 mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

limb grasping ( J:82238 )

• when the mice are lifted up by their tail, the hind limbs tend to clutch to their body

tremors ( J:82238 )

• intense body tremor with intermittent hind limb spasms

ataxia ( J:82238 )

• trunk swaying and staggering forward movements (cerebellar ataxia)

impaired balance ( J:82238 )

• animals lose balance occasionally, but it is quickly regained

abnormal posture ( J:82238 )

• hind limbs of mutants are set wide apart during movement and rest

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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