Phenotypes associated with this allele

• Allele Symbol: Cacna1g^tm1Stl
• Allele Name: targeted mutation 1, Susumu Tonegawa
• Allele ID: MGI:3530499
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Camk2a-cre)CW2Stl/0	involves: C57BL/6	MGI:3531191
cn2	Cacna1g^tm1Stl/Cacna1g^tm1Stl Tg(Kcnc2-cre)K128Stl/0	involves: C57BL/6	MGI:3531192

Genotype
MGI:3531191

cn1

• Allelic Composition: Cacna1g^tm1Stl/Cacna1g^tm1Stl; Tg(Camk2a-cre)CW2Stl/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:96099 )

N • no disruption of sleep patterns or reduction in total sleep are seen

Genotype
MGI:3531192

cn2

• Allelic Composition: Cacna1g^tm1Stl/Cacna1g^tm1Stl; Tg(Kcnc2-cre)K128Stl/0
• Genetic Background: involves: C57BL/6

behavior/neurological

abnormal sleep pattern ( J:96099 )

• during the light period mutants display fragmented sleep with frequent brief wakenings, more total wake bouts, and non-REM bouts are much shorter

• increased delta wave power is seen during non-REM sleep

fragmentation of sleep/wake states ( J:96099 )