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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pik3cdGt(OST451938)Lex
gene trap OST451938, Lexicon Genetics
MGI:3530101
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pik3cdGt(OST451938)Lex/Pik3cdGt(OST451938)Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609815


Genotype
MGI:3609815
hm1
Allelic
Composition		 Pik3cdGt(OST451938)Lex/Pik3cdGt(OST451938)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3cdGt(OST451938)Lex mutation (2 available); any Pik3cd mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased leukocyte cell number ( J:103485 )
• median white blood cell count is increased
increased lymphocyte cell number ( J:103485 )
• absolute lymphocyte counts are increased
decreased IgG1 level ( J:103485 )
• following ovalbumin challenge mean serum IgG1 response is decreased

hematopoietic system
increased leukocyte cell number ( J:103485 )
• median white blood cell count is increased
increased lymphocyte cell number ( J:103485 )
• absolute lymphocyte counts are increased
decreased IgG1 level ( J:103485 )
• following ovalbumin challenge mean serum IgG1 response is decreased




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory