All Phenotypes Mtor<Gt(OST92090)Lex> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mtor^{Gt(OST92090)Lex}
gene trap OST92090, Lexicon Genetics
MGI:3529989

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mtor^{Gt(OST92090)Lex}/Mtor^{Gt(OST92090)Lex}	involves: 129S5/SvEvBrd	MGI:3802637
cx2	Mtor^{Gt(OST92090)Lex}/Mtor⁺ Pten^tm1Rps/Pten⁺	involves: 129S1/Sv * 129S5/SvEvBrd * C57BL/6	MGI:4848141

Allelic Composition	Mtor^{Gt(OST92090)Lex}/Mtor^{Gt(OST92090)Lex}
Genetic Background	involves: 129S5/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtor^{Gt(OST92090)Lex} mutation (1 available); any Mtor mutation (117 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

absent inner cell mass proliferation ( J:137592 )

• inner cell mass explants fail to expand in culture unlike wild-type explants

abnormal trophoblast giant cell morphology ( J:137592 )

• explants fail to expand in culture unlike wild-type explants

cellular

absent inner cell mass proliferation ( J:137592 )

• inner cell mass explants fail to expand in culture unlike wild-type explants

Allelic Composition	Mtor^{Gt(OST92090)Lex}/Mtor⁺ Pten^tm1Rps/Pten⁺
Genetic Background	involves: 129S1/Sv * 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtor^{Gt(OST92090)Lex} mutation (1 available); any Mtor mutation (117 available)
Pten^tm1Rps mutation (0 available); any Pten mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

extended life span ( J:144810 )

• double mutants live longer than single heterozygous Pten mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24