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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gje1Mhdaaey12
Martin Hrabe de Angelis abnormal eyes 12
MGI:3529958
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gje1Mhdaaey12/Gje1Mhdaaey12 involves: C3HeB/FeJ MGI:3797648
ht2
Gje1Mhdaaey12/Gje1+ C3HeB/FeJ-Gje1Mhdaaey12/Ieg MGI:3716889
ht3
Gje1Mhdaaey12/Gje1+ involves: C3HeB/FeJ MGI:3797647


Genotype
MGI:3797648
hm1
Allelic
Composition
Gje1Mhdaaey12/Gje1Mhdaaey12
Genetic
Background
involves: C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gje1Mhdaaey12 mutation (1 available); any Gje1 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• mice exhibit empty lens consisting of only an envelope
• the lens grows together (fuses) with other ocular tissues
• after lens vesicle formation, lens fibers fail to elongate from the posterior part of the lens and the connections between the lens fibers and the lens epithelium are disrupted
• the lens grows together (fuses) with other ocular tissues
• primary lens fibers fail to elongate
• mice exhibit retinal folding and poor differentiation




Genotype
MGI:3716889
ht2
Allelic
Composition
Gje1Mhdaaey12/Gje1+
Genetic
Background
C3HeB/FeJ-Gje1Mhdaaey12/Ieg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gje1Mhdaaey12 mutation (1 available); any Gje1 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye




Genotype
MGI:3797647
ht3
Allelic
Composition
Gje1Mhdaaey12/Gje1+
Genetic
Background
involves: C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gje1Mhdaaey12 mutation (1 available); any Gje1 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• mice exhibit corneal thickening
• elongating lens fibers fail to reach the anterior epithelium
• mice exhibit polar lens opacity





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory