All Phenotypes Pzp2<tm1Lex> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pzp2^tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3529167

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pzp2^tm1Lex/Pzp2^tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:3609833

Allelic Composition	Pzp2^tm1Lex/Pzp2^tm1Lex
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pzp2^tm1Lex mutation (2 available); any Pzp2 mutation (77 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

increased bone mineral density ( J:103485 )

• bone mineral density is increased

behavior/neurological

decreased locomotor activity ( J:103485 )

• in homozygous females activity is decreased during a 10 hour habituation period and in the home cage during the dark phase

cardiovascular system

decreased heart rate ( J:103485 )

• decreased mean heart rates are seen in homozygous males

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24