Phenotypes associated with this allele

• Allele Symbol: Acsl3^{Gt(OST148301)Lex}
• Allele Name: gene trap OST148301, Lexicon Genetics
• Allele ID: MGI:3529071
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Acsl3^Gt(OST148301)Lex/Acsl3^Gt(OST148301)Lex	B6;129S5-Acsl3^Gt(OST148301)Lex/Orl	MGI:5427958

Genotype
MGI:5427958

hm1

• Allelic Composition: Acsl3^{Gt(OST148301)Lex}/Acsl3^{Gt(OST148301)Lex}
• Genetic Background: B6;129S5-Acsl3^{Gt(OST148301)Lex}/Orl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

abnormal postnatal growth/weight/body size ( J:82809 )

♂ • male mutants exhibit decreased total tissue mass

decreased lean body mass ( J:82809 )

♂ • male mutants exhibit decreased lean body mass

decreased body weight ( J:82809 )

♂ • male mutants exhibit decreased mean body weight

decreased body length ( J:82809 )

♂ • male mutants exhibit decreased mean body length

postnatal growth retardation ( J:82809 )

♂ • male mutants exhibit signs of growth retardation

hematopoietic system

decreased B cell number ( J:82809 )

• decreased peripheral blood percentages of B cells

increased CD4-positive, alpha-beta T cell number ( J:82809 )

• increased peripheral blood percentages of CD4 cells

immune system

decreased B cell number ( J:82809 )

• decreased peripheral blood percentages of B cells

increased CD4-positive, alpha-beta T cell number ( J:82809 )

• increased peripheral blood percentages of CD4 cells

abnormal humoral immune response ( J:82809 )

• decreased IgG1 response to ovalbumin