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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcna6tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3528817
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kcna6tm1Lex/Kcna6tm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:3609818


Genotype
MGI:3609818
hm1
Allelic
Composition		 Kcna6tm1Lex/Kcna6tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcna6tm1Lex mutation (1 available); any Kcna6 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased thermal nociceptive threshold ( J:103485 )
• a decreased pain response is seen in the hot plate test

homeostasis/metabolism
increased circulating triglyceride level ( J:103485 )
• seen in homozygous females




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory