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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Trmq3FVB/N
FVB/N
MGI:3528157
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Trmq3FVB/N/Trmq3FVB/N involves: DBA/1J * FVB/N MGI:3695160
ht2
 		Trmq3DBA/1J/Trmq3FVB/N involves: DBA/1J * FVB/N MGI:3695161
ot3
 		Trmq3FVB/N/? involves: DBA/1J * FVB/N MGI:3528175


Genotype
MGI:3695160
hm1
Allelic
Composition		 Trmq3FVB/N/Trmq3FVB/N
Genetic
Background		 involves: DBA/1J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal CD4-positive, alpha beta T cell morphology ( J:116665 )
• increased CD4:CD8 ratios in collagen-immunized arthritic mice

immune system
abnormal CD4-positive, alpha beta T cell morphology ( J:116665 )
• increased CD4:CD8 ratios in collagen-immunized arthritic mice




Genotype
MGI:3695161
ht2
Allelic
Composition		 Trmq3DBA/1J/Trmq3FVB/N
Genetic
Background		 involves: DBA/1J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal CD4-positive, alpha beta T cell morphology ( J:116665 )
• increased CD4:CD8 ratios in collagen-immunized arthritic mice

immune system
abnormal CD4-positive, alpha beta T cell morphology ( J:116665 )
• increased CD4:CD8 ratios in collagen-immunized arthritic mice




Genotype
MGI:3528175
ot3
Allelic
Composition		 Trmq3FVB/N/?
Genetic
Background		 involves: DBA/1J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal T cell proliferation ( J:94347 )
• increased CD4:CD8 T cell ratio in collagen-immunized arthritic mice
abnormal CD4-positive, alpha beta T cell morphology ( J:94347 )
• increased CD4:CD8 ratio in collagen-immunized arthritic mice

immune system
abnormal T cell proliferation ( J:94347 )
• increased CD4:CD8 T cell ratio in collagen-immunized arthritic mice
abnormal CD4-positive, alpha beta T cell morphology ( J:94347 )
• increased CD4:CD8 ratio in collagen-immunized arthritic mice

cellular
abnormal T cell proliferation ( J:94347 )
• increased CD4:CD8 T cell ratio in collagen-immunized arthritic mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory