Phenotypes associated with this allele

• Allele Symbol: Aqp7^tm1Tfun
• Allele Name: targeted mutation 1, Tohru Funahashi
• Allele ID: MGI:3526441
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aqp7^tm1Tfun/Aqp7^tm1Tfun	B6N.129X1-Aqp7^tm1Tfun	MGI:3526576

Genotype
MGI:3526576

hm1

• Allelic Composition: Aqp7^tm1Tfun/Aqp7^tm1Tfun
• Genetic Background: B6N.129X1-Aqp7^tm1Tfun

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

hypoglycemia ( J:95278 )

• after a 12 hour fast, mutants become hypoglycemic

decreased circulating glycerol level ( J:95278 )

• plasma glycerol levels are lower in both the fed and fasted states and glycerol levels do not increase when mutants are fasted

• increases in plasma glycerol levels after treatment with a beta3-andregenic agonist are impaired

increased glycerol level ( J:95278 )

• glycerol concentration is increased in adipose tissue in fasted mutants