All Phenotypes Rnf17<tm1Jw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rnf17^tm1Jw
targeted mutation 1, Jeremy Wang
MGI:3526166

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf17^tm1Jw/Rnf17^tm1Jw	involves: 129 * C57BL/6	MGI:3606183

Allelic Composition	Rnf17^tm1Jw/Rnf17^tm1Jw
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf17^tm1Jw mutation (0 available); any Rnf17 mutation (78 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

azoospermia ( J:101737 )

small seminiferous tubules ( J:101737 )

small testis ( J:101737 )

• at 8 weeks of age the testes are 25% smaller than wild-type

arrest of spermatogenesis ( J:101737 )

• spermatogenesis arrests at the round spermatid stage and large multinucleated degenerating cells are seen in the seminiferous tubules

male infertility ( J:101737 )

• males but not females are infertile

endocrine/exocrine glands

small seminiferous tubules ( J:101737 )

small testis ( J:101737 )

• at 8 weeks of age the testes are 25% smaller than wild-type

cellular

azoospermia ( J:101737 )

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