Phenotypes associated with this allele

• Allele Symbol: Ptcra^tm1Bjf
• Allele Name: targeted mutation 1, B J Fowlkes
• Allele ID: MGI:3526158
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ptcra^tm1Bjf/Ptcra^+	involves: 129X1/SvJ	MGI:3805108

Genotype
MGI:3805108

ht1

• Allelic Composition: Ptcra^tm1Bjf/Ptcra⁺
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal T cell differentiation ( J:94338 )

• 30% fewer DN4 T cells are in S+G2/M phase of the cell cycle than in wild-type mice

decreased double-negative T cell number ( J:94338 )

• reduced 30% to 40% compared to in wild-type mice

decreased single-positive T cell number ( J:94338 )

• reduced 30% to 40% compared to in wild-type mice

hematopoietic system

abnormal T cell differentiation ( J:94338 )

• 30% fewer DN4 T cells are in S+G2/M phase of the cell cycle than in wild-type mice

decreased double-negative T cell number ( J:94338 )

• reduced 30% to 40% compared to in wild-type mice

decreased single-positive T cell number ( J:94338 )

• reduced 30% to 40% compared to in wild-type mice