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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Homer3tm1Mhd
targeted mutation 1, Marlin H Dehoff
MGI:3526157
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Homer3tm1Mhd/Homer3tm1Mhd B6.129-Homer3tm1Mhd MGI:3716980
cx2
 		Homer2tm1Mhd/Homer2tm1Mhd
Homer3tm1Mhd/Homer3tm1Mhd 		involves: 129S1/Sv * 129X1/SvJ MGI:5461825


Genotype
MGI:3716980
hm1
Allelic
Composition		 Homer3tm1Mhd/Homer3tm1Mhd
Genetic
Background		 B6.129-Homer3tm1Mhd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Homer3tm1Mhd mutation (1 available); any Homer3 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:96554 )
N
• mice exhibit equivalent cocaine place condition and cocaine-induce locomotor hyperactivity compared to wild-type mice




Genotype
MGI:5461825
cx2
Allelic
Composition		 Homer2tm1Mhd/Homer2tm1Mhd
Homer3tm1Mhd/Homer3tm1Mhd
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Homer2tm1Mhd mutation (1 available); any Homer2 mutation (22 available)
Homer3tm1Mhd mutation (1 available); any Homer3 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal nociception after inflammation ( J:191366 )
• formalin-treated mice exhibit greater response to pain during the second phase, but not the first phase, compared with wild-type mice




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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory