Phenotypes associated with this allele

• Allele Symbol: Gsdma3^Rco2
• Allele Name: Reduced coat 2
• Allele ID: MGI:3526126
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Gsdma3^Rco2/Gsdma3^+	C3HeB/FeJ-Gsdma3^Rco2	MGI:3586854

Genotype
MGI:3586854

ht1

• Allelic Composition: Gsdma3^Rco2/Gsdma3⁺
• Genetic Background: C3HeB/FeJ-Gsdma3^Rco2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

integument phenotype ( J:93938 )

N • whiskers are unaffected

abnormal coat appearance ( J:93938 )

abnormal hair growth ( J:93938 )

• appearance is normal until 3 weeks of age when hair loss proceeds from head to tail

• second coat is sparse with fewer zigzag hairs and mainly long hairs

• by 6 months of age, mice are hairless except for the facial region

abnormal hair follicle development ( J:93938 )

• development is abnormal due to protracted catagen

• sebaceous glands normally associated with hair follicles are absent

• hair loss is coincidental with the first active growing phase

abnormal skin condition ( J:93938 )

• exposed skin on the head following hair loss was red, then turned gray

• skin of aged mutants is gray and has an increase in dermal fibrous tissue