Phenotypes associated with this allele

• Allele Symbol: Frs2^tm2Schl
• Allele Name: targeted mutation 2, Joseph Schlessinger
• Allele ID: MGI:3521971
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Frs2^tm2Schl/Frs2^tm2Schl	involves: 129S2/SvPas	MGI:3717721

Genotype
MGI:3717721

hm1

• Allelic Composition: Frs2^tm2Schl/Frs2^tm2Schl
• Genetic Background: involves: 129S2/SvPas

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Variable penetrance of eye defects in Frs2^tm1Schl/Frs2^tm1Schl and small body size in Frs2^tm2Schl/Frs2^tm2Schl mice

growth/size/body

decreased fetal size ( J:94724 )

• smaller than wild-type at E14.4

nervous system

nervous system phenotype ( J:102930 )

N • mice have normal head and brain size

craniofacial

craniofacial phenotype ( J:102930 )

N • mice have normal head and brain size

vision/eye

vision/eye phenotype ( J:94724 )

N • evagination of the optic vesicle appears normal at embryonic day 9.5