Analysis Tools
nervous system
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• trajectories of sensory cutaneous nerves in the thoracic body wall appear intact but are highly disorganized and severely defasciculated, however homozygotes appear healthy and fertile
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Allele Symbol Allele Name Allele ID |
Erbb2tm7(Erbb2)Mul targeted mutation 7, William J Muller MGI:3521860 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• trajectories of sensory cutaneous nerves in the thoracic body wall appear intact but are highly disorganized and severely defasciculated, however homozygotes appear healthy and fertile
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• die shortly after birth struggling unsuccessfully to breathe
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• phrenic nerves are thinned, disorganized, and discontinuous or incomplete and they lack an apparent main nerve trunk from which smaller presynaptic branches originate
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• diaphragm muscle is very poorly innervated by the phrenic nerve
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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