About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gucy2dtm1Sdm
targeted mutation 1, Steven D Munger
MGI:3521821
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gucy2dtm1Sdm/Gucy2dtm1Sdm involves: 129S1/Sv * 129X1/SvJ MGI:3723601


Genotype
MGI:3723601
hm1
Allelic
Composition		 Gucy2dtm1Sdm/Gucy2dtm1Sdm
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gucy2dtm1Sdm mutation (0 available); any Gucy2d mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal olfactory bulb periglomerular cell morphology ( J:124965 )
• tyrosine hydrolase immunoreactivity is nearly absent in olfactory bulb periglomular cells whereas TH immunoreactivity is present in all beta-galactosidase positive cell in heterozygotes

taste/olfaction
abnormal olfactory system physiology ( J:124965 )
• as measured by electroolfactogram, uroguanylin- and guanylin-evoked potentials are abolished




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory