All Phenotypes Igf2<tm3Wrk> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Igf2^tm3Wrk
targeted mutation 3, Wolf Reik
MGI:3521799

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Igf2^tm3Wrk/Igf2⁺	Not Specified	MGI:3529534

Allelic Composition	Igf2^tm3Wrk/Igf2⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igf2^tm3Wrk mutation (0 available); any Igf2 mutation (29 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body size ( J:94521 )

• following paternal transmission, mutants were 17% smaller at birth than wild-types

• following maternal transmission, mice were normal in size and expressed normal levels of Igf2 from their paternal allele, while the maternal allele remained silent

cellular

maternal imprinting ( J:94521 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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