Phenotypes associated with this allele

• Allele Symbol: Tg(KRT14-HPV16E7)2326Plam
• Allele Name: transgene insertion 2326, Paul F Lambert
• Allele ID: MGI:3514315
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(KRT14-HPV16E7)2326Plam/0	involves: FVB/N	MGI:3606962

Genotype
MGI:3606962

tg1

• Allelic Composition: Tg(KRT14-HPV16E7)2326Plam/0
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased sebaceous gland tumor incidence ( J:86018 )

• beginning around 9 months of age, two classes of skin tumors are seen small highly keratotic lesions representing low-grade squamous cell carcinomas and large, cystic but nonkeratotic lesions representing aggressive sebaceous epitheliomas

increased skin squamous cell carcinoma incidence ( J:86018 )

• beginning around 9 months of age, small highly keratotic lesions representing low-grade squamous cell carcinomas are seen in the skin

endocrine/exocrine glands

increased sebaceous gland tumor incidence ( J:86018 )

• beginning around 9 months of age, two classes of skin tumors are seen small highly keratotic lesions representing low-grade squamous cell carcinomas and large, cystic but nonkeratotic lesions representing aggressive sebaceous epitheliomas

growth/size/body

epithelioid cyst ( J:86018 )

• beginning around 9 months of age, large, cystic but nonkeratotic lesions representing aggressive sebaceous epitheliomas and containing large accumulations of sebum are seen in the skin

vision/eye

developmental cataract ( J:86018 )

• small bilateral cataracts are seen at birth

integument

increased sebaceous gland tumor incidence ( J:86018 )

• beginning around 9 months of age, two classes of skin tumors are seen small highly keratotic lesions representing low-grade squamous cell carcinomas and large, cystic but nonkeratotic lesions representing aggressive sebaceous epitheliomas

epithelioid cyst ( J:86018 )

• beginning around 9 months of age, large, cystic but nonkeratotic lesions representing aggressive sebaceous epitheliomas and containing large accumulations of sebum are seen in the skin

sparse hair ( J:86018 )

• mice appear scruffy with less dense fur

matted coat ( J:86018 )

• the fur often appears greasy and matted

greasy coat ( J:86018 )

• the fur often appears greasy and matted

increased skin squamous cell carcinoma incidence ( J:86018 )

• beginning around 9 months of age, small highly keratotic lesions representing low-grade squamous cell carcinomas are seen in the skin