All Phenotypes Lrrk2<tm1Tmd> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lrrk2^tm1Tmd
targeted mutation 1, Ted Dawson
MGI:3514169

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrrk2^tm1Tmd/Lrrk2^tm1Tmd	involves: 129S/SvEv * C57BL/6	MGI:3834936

Allelic Composition	Lrrk2^tm1Tmd/Lrrk2^tm1Tmd
Genetic Background	involves: 129S/SvEv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrk2^tm1Tmd mutation (0 available); any Lrrk2 mutation (162 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• fewer than expected mice are viable (no time of death given)

behavior/neurological

increased grooming behavior ( J:157100 )

• excessive resulting in alopecia of the muzzle and head

integument

alopecia ( J:157100 )

• centered on the muzzle and head due to excessive grooming

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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