Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MtapGt(RRK081)Byg mutation
(1 available);
any
Mtap mutation
(18 available)
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mortality/aging
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• homozygotes die by E8.5
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MtapGt(RRK081)Byg mutation
(1 available);
any
Mtap mutation
(18 available)
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cardiovascular system
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• at 4 to 7 months of age, some heterozygotes display polyarteritis nodosa; however, no consistent phenotype is observed
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liver/biliary system
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• at 4 to 7 months of age, some heterozygotes display unusual vacuoles in the liver; however, no consistent phenotype is observed
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respiratory system
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• at 4 to 7 months of age, some heterozygotes display dilated bronchi; however, no consistent phenotype is observed
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immune system
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• at 4 to 7 months of age, some heterozygotes display polyarteritis nodosa; however, no consistent phenotype is observed
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hearing/vestibular/ear
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N |
• at 5 and a half weeks of age, heterozygotes display normal cochlear function, with no significant differences in ABR and DPOAE thresholds relative to wild-type mice
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Allelic
Composition |
MtapGt(RRK081)Byg/Mtap+
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Genetic
Background |
involves: 129P2/OlaHsd * CBA/CaJ |
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MtapGt(RRK081)Byg mutation
(1 available);
any
Mtap mutation
(18 available)
|
|
|
hearing/vestibular/ear
|
N |
• at 5 and a half weeks and at 6 months of age, heterozygotes show no significant differences in ABR and DPOAE thresholds relative to wild-type mice
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Analysis Tools
