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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm1(Akt1/EGFP)Glas
targeted mutation 1, David J Glass
MGI:3512295
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Gt(ROSA)26Sortm1(Akt1/EGFP)Glas/Gt(ROSA)26Sor+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3512550


Genotype
MGI:3512550
cn1
Allelic
Composition
Gt(ROSA)26Sortm1(Akt1/EGFP)Glas/Gt(ROSA)26Sor+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Akt1/EGFP)Glas mutation (0 available); any Gt(ROSA)26Sor mutation (942 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• after treatment with tamoxifen a significant decrease in adipose tissue deposits is seen

muscle
• a significant increase in mean skeletal muscle fiber diameter is seen in tamoxifen-treated mutants however the number of muscle fibers does not increase
• after treatment with tamoxifen a significant increase in muscle weight is seen
• after treatment with tamoxifen a significant increase in skeletal muscle size is seen





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory