Phenotypes associated with this allele

• Allele Symbol: Myh9^{Gt(Betageo-btk)1Dash}
• Allele Name: gene trap 1, Tadashi Matsushita
• Allele ID: MGI:3511350
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myh9^Gt(Betageo-btk)1Dash/Myh9^Gt(Betageo-btk)1Dash	involves: 129X1/SvJ * C57BL/6	MGI:3511799
ht2	Myh9^Gt(Betageo-btk)1Dash/Myh9^+	involves: 129X1/SvJ * C57BL/6	MGI:3511800

Genotype
MGI:3511799

hm1

• Allelic Composition: Myh9^{Gt(Betageo-btk)1Dash}/Myh9^{Gt(Betageo-btk)1Dash}
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:94067 )

• no viable homozygous embryos are seen after E7.5

Genotype
MGI:3511800

ht2

• Allelic Composition: Myh9^{Gt(Betageo-btk)1Dash}/Myh9⁺
• Genetic Background: involves: 129X1/SvJ * C57BL/6

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:94067 )

• at 10 weeks of age, 2 of 6 heterozygous mice showed a decreased response as shown by an increased threshold for sound pressure levels

impaired hearing ( J:94067 )

• 2 out of 6 heterozygotes displayed hearing loss

hematopoietic system

hematopoietic system phenotype ( J:94067 )

N • no abnormalities were detected in red or white blood cell counts, hemoglobin, hematocrit, or megakaryocytes

renal/urinary system

renal/urinary system phenotype ( J:94067 )

N • no defects were detected in the kidneys of 4-5 week old or 12 week old heterozygotes