All Phenotypes Prdm1<tm1Nutt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prdm1^tm1Nutt
targeted mutation 1, Stephen L Nutt
MGI:3510704

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdm1^tm1Nutt/Prdm1^tm1Nutt	involves: C57BL/6	MGI:3510954
cx2	Clptm1l^{tm1d(EUCOMM)Wtsi}/Clptm1l^{tm1d(EUCOMM)Wtsi} Prdm1^tm1Nutt/Prdm1⁺	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N	MGI:6281129
cx3	Itm2c^em1Nutt/Itm2c^em1Nutt Prdm1^tm1Nutt/Prdm1⁺	involves: C57BL/6 * C57BL/6J	MGI:6281134
cx4	Plpp5^tm1(KOMP)Mbp/Plpp5^tm1(KOMP)Mbp Prdm1^tm1Nutt/Prdm1⁺	involves: C57BL/6 * C57BL/6N	MGI:6281123

Allelic Composition	Prdm1^tm1Nutt/Prdm1^tm1Nutt
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm1^tm1Nutt mutation (1 available); any Prdm1 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:93944 )

• homozygotes die late in gestation

Allelic Composition	Clptm1l^{tm1d(EUCOMM)Wtsi}/Clptm1l^{tm1d(EUCOMM)Wtsi} Prdm1^tm1Nutt/Prdm1⁺
Genetic Background	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N
Cell Lines	EPD0460_2_E07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clptm1l^{tm1d(EUCOMM)Wtsi} mutation (0 available); any Clptm1l mutation (34 available)
Prdm1^tm1Nutt mutation (1 available); any Prdm1 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:265892 )

N	• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls

Allelic Composition	Itm2c^em1Nutt/Itm2c^em1Nutt Prdm1^tm1Nutt/Prdm1⁺
Genetic Background	involves: C57BL/6 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itm2c^em1Nutt mutation (0 available); any Itm2c mutation (19 available)
Prdm1^tm1Nutt mutation (1 available); any Prdm1 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:265892 )

N	• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls

Allelic Composition	Plpp5^tm1(KOMP)Mbp/Plpp5^tm1(KOMP)Mbp Prdm1^tm1Nutt/Prdm1⁺
Genetic Background	involves: C57BL/6 * C57BL/6N
Cell Lines	DEPD00512_4_E01

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plpp5^tm1(KOMP)Mbp mutation (0 available); any Plpp5 mutation (12 available)
Prdm1^tm1Nutt mutation (1 available); any Prdm1 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:265892 )

N	• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls

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