Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lat2tm1Mal mutation
(1 available);
any
Lat2 mutation
(19 available)
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immune system
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• detectable in 5 of 7 individuals
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lat2tm1Mal mutation
(1 available);
any
Lat2 mutation
(19 available)
|
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immune system
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• after antigen challenge, serum histamine levels were significantly higher than normal
• mast cell numbers were normal
• enhanced degranulation response seen in bone marrow mast cells
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hematopoietic system
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• after antigen challenge, serum histamine levels were significantly higher than normal
• mast cell numbers were normal
• enhanced degranulation response seen in bone marrow mast cells
|
immune system
|
• detectable in 5 of 7 individuals
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lat2tm1Mal mutation
(1 available);
any
Lat2 mutation
(19 available)
Lattm2.1Mal mutation
(0 available);
any
Lat mutation
(9 available)
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immune system
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• secretory responses of bone marrow mast cells were partially inhibited
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hematopoietic system
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• secretory responses of bone marrow mast cells were partially inhibited
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