Phenotypes associated with this allele

• Allele Symbol: Golga1^awag
• Allele Name: ages with abnormal gait
• Allele ID: MGI:3510600
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Golga1^awag/Golga1^awag	B6.Cg-Golga1^awag Tyr^c-2J/GrsrJ	MGI:3574837

Genotype
MGI:3574837

hm1

• Allelic Composition: Golga1^awag/Golga1^awag
• Genetic Background: B6.Cg-Golga1^awag Tyr^c-2J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

limb grasping ( J:94744 )

• when lifted by the tail, mice do not splay hind legs out, but instead they hold their legs in a bowlegged umbrella like way and arch their backs

tremors ( J:94744 )

• distinct tremor when walking that first appears around 2 months of age

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:94744 )

• variable penetrance; ABR assesment at 3 months indicated that two mutants had hearing loss; other mice at 6 months had normal or nearly normal hearing

vision/eye

abnormal cornea morphology ( J:94744 )

• corneal holes were observed, but is probably due to background strain and not the awag mutation

cataract ( J:94744 )

• cataracts were observed, but is probably due to background strain and not the awag mutation

nervous system

hydrocephaly ( J:94744 )

• mild hydrocephalus observed in three animals, assumed to be a strain background occurence