Phenotypes associated with this allele

• Allele Symbol: Tg(Pbsn-Cdc37)1Stp
• Allele Name: transgene insertion 1, Lilia Stepanova
• Allele ID: MGI:3505712
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Pbsn-Cdc37)1Stp/0	involves: C57BL/6 * DBA/2 * ICR	MGI:3839897

Genotype
MGI:3839897

tg1

• Allelic Composition: Tg(Pbsn-Cdc37)1Stp/0
• Genetic Background: involves: C57BL/6 * DBA/2 * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal prostate gland morphology ( J:93695 )

♂ • as early as 6 months of age, 18% of mice exhibit prostate growth-related abnormalities unlike in wild-type mice

♂ • by 12 months of age 80% of mice exhibit prostate growth-related abnormalities unlike in wild-type mice

♂ • mice exhibit stromal fibrosis in the prostate

prostate gland epithelial hyperplasia ( J:93695 )

♂ • mice exhibit ventral prostate epithelial hyperplasia frequently accompanied by necrosis unlike in wild-type mice

♂ • epithelial hypoplasia involve greater than 50% of acini

♂ • epithelial hypoplasia develops gradually

reproductive system

abnormal prostate gland morphology ( J:93695 )

♂ • as early as 6 months of age, 18% of mice exhibit prostate growth-related abnormalities unlike in wild-type mice

♂ • by 12 months of age 80% of mice exhibit prostate growth-related abnormalities unlike in wild-type mice

♂ • mice exhibit stromal fibrosis in the prostate

prostate gland epithelial hyperplasia ( J:93695 )

♂ • mice exhibit ventral prostate epithelial hyperplasia frequently accompanied by necrosis unlike in wild-type mice

♂ • epithelial hypoplasia involve greater than 50% of acini

♂ • epithelial hypoplasia develops gradually