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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lin9+
wild type
MGI:3505559
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
Lin9tm1.1Sgau/Lin9+ 		involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL MGI:4819583
cx2
 		Cdk4tm1Kiyo/Cdk4+
Lin9tm1Orc/Lin9+ 		involves: 129S1/Sv MGI:3712956


Genotype
MGI:4819583
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
Lin9tm1.1Sgau/Lin9+
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT)Brn mutation (1 available); any Gt(ROSA)26Sor mutation (1060 available)
Lin9tm1.1Sgau mutation (0 available); any Lin9 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal mitotic spindle assembly checkpoint ( J:162678 )
• mouse embryonic fibroblasts treated with tamoxifen and nocodazole exhibit reduced cell cycle arrest compared with similarly treated wild-type mice




Genotype
MGI:3712956
cx2
Allelic
Composition		 Cdk4tm1Kiyo/Cdk4+
Lin9tm1Orc/Lin9+
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk4tm1Kiyo mutation (0 available); any Cdk4 mutation (57 available)
Lin9tm1Orc mutation (0 available); any Lin9 mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell cycle ( J:111333 )
• number of MEF cells in S-phase is increased by 2.3-fold

immune system
decreased susceptibility to autoimmune diabetes ( J:111333 )
• mice do not develop early onset diabetes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory