All Phenotypes Kcnj11<Y12stop> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kcnj11^Y12stop
Tyr12stop
MGI:3056474

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcnj11^Y12stop/Kcnj11^Y12stop	involves: BALB/c * C3H/HeH	MGI:3717752

Allelic Composition	Kcnj11^Y12stop/Kcnj11^Y12stop
Genetic Background	involves: BALB/c * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnj11^Y12stop mutation (0 available); any Kcnj11 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

decreased glucagon secretion ( J:122088 )

• at low glucose concentrations glucagons secretion is suppressed

increased insulin secretion ( J:122088 )

• at low glucose concentrations insulin secretion is elevated

homeostasis/metabolism

decreased glucagon secretion ( J:122088 )

• at low glucose concentrations glucagons secretion is suppressed

increased insulin secretion ( J:122088 )

• at low glucose concentrations insulin secretion is elevated

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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