All Phenotypes Ept MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ept
elliptic
MGI:3055805

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ept/Ept	involves: C57BL/6J * DBA/2J	MGI:5882326
ht2	Ept/Ept⁺	C57BL/6J-Ept/KjnJ	MGI:5882323

Allelic Composition	Ept/Ept
Genetic Background	involves: C57BL/6J * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ept mutation (1 available); any Ept mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

circling ( J:239807 )

• homozygotes generated on a (C57BL/6J x DBA/2J)F2 background are viable and fertile and display the same moderate circling phenotype as that found in heterozygotes on a pure C57BL/6J background, and no additional outward phenotypes are evident

Allelic Composition	Ept/Ept⁺
Genetic Background	C57BL/6J-Ept/KjnJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ept mutation (1 available); any Ept mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired swimming ( J:239807 )

• heterozygotes have difficulty orienting in water and when at the surface they swim in circles

circling ( J:239807 )

• heterozygotes display a moderate circling phenotype indicative of a vestibular defect

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:239807 )

N	• despite the vestibular defect no hearing impairment was found by ABR at 1, 2, or 3 months of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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