Phenotypes associated with this allele

• Allele Symbol: Dmbx1^tm1Bhr
• Allele Name: targeted mutation 1, Richard R Behringer
• Allele ID: MGI:3055282
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dmbx1^tm1Bhr/Dmbx1^tm1Bhr	involves: 129S4/SvJae * C57BL/6	MGI:3055294

Genotype
MGI:3055294

hm1

• Allelic Composition: Dmbx1^tm1Bhr/Dmbx1^tm1Bhr
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality ( J:92785 )

• some homozygotes die postnatally before P9 probably as a result of impaired milk intake

behavior/neurological

absent gastric milk in neonates ( J:92785 )

• little or no milk is found in some mutant pups stomachs

growth/size/body

postnatal growth retardation ( J:92785 )

• impaired postnatal growth with reduced weight gain is seen probably as a result of impaired milk intake

reproductive system

reduced female fertility ( J:92785 )

♀ • female but not male homozygotes have fewer surviving offspring probably as a result of a nursing defect although maternal nurturing behaviors are normal and milk production is seen