Phenotypes associated with this allele

• Allele Symbol: Ereg^tm1Sawa
• Allele Name: targeted mutation 1, Senji Shirasawa
• Allele ID: MGI:3054792
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ereg^tm1Sawa/Ereg^tm1Sawa	involves: 129X1/SvJ * C57BL/6J	MGI:3054826

Genotype
MGI:3054826

hm1

• Allelic Composition: Ereg^tm1Sawa/Ereg^tm1Sawa
• Genetic Background: involves: 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Pathology of the skin legions in Ereg^tm1Sawa/Ereg^tm1Sawa mice

immune system

dermatitis ( J:92618 )

• homozygotes develop chronic dermatitis by 5 months of age with focal skin alterations seen first on the ears or face then spreading to the neck

• the incidence of dermatitis increases from about 20% to 75% as the mice age (9 months to 15 months)

integument

dermatitis ( J:92618 )

• homozygotes develop chronic dermatitis by 5 months of age with focal skin alterations seen first on the ears or face then spreading to the neck

• the incidence of dermatitis increases from about 20% to 75% as the mice age (9 months to 15 months)