About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(VIM-Tag)3Pau
transgene insertion 3, Denise Pauline
MGI:3052038
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(VIM-Tag)3Pau/0 either: (involves: C57BL/6 * CBA * SJL/J) or (involves: C57BL/6 * SJL/J) MGI:3720109
tg2
 		Tg(VIM-Tag)3Pau/0 involves: C57BL/6 * SJL/J MGI:3720107


Genotype
MGI:3720109
tg1
Allelic
Composition		 Tg(VIM-Tag)3Pau/0
Genetic
Background		 either: (involves: C57BL/6 * CBA * SJL/J) or (involves: C57BL/6 * SJL/J)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:92226 )
• transgenics that survive beyond 3 weeks die between 60 and 90 days of age
postnatal lethality, incomplete penetrance ( J:92226 )
• one third of the transgenic mice die within 2-3 weeks of birth

renal/urinary system
glomerulonephritis ( J:92226 )
• exhibit diffuse hypercellular glomeruli and tubule dilation characteristic of proliferative glomerulonephritis

nervous system
abnormal cerebral cortex morphology ( J:92226 )
• infiltration of the cortex by glial cells is seen

immune system
glomerulonephritis ( J:92226 )
• exhibit diffuse hypercellular glomeruli and tubule dilation characteristic of proliferative glomerulonephritis




Genotype
MGI:3720107
tg2
Allelic
Composition		 Tg(VIM-Tag)3Pau/0
Genetic
Background		 involves: C57BL/6 * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
thymus hyperplasia ( J:91542 )
• at 4-6 weeks of age the thymus contains about 20-fold more cells than wild-type
increased double-negative T cell number ( J:91542 )
• the total number of DN cells is increased 115-fold

immune system
thymus hyperplasia ( J:91542 )
• at 4-6 weeks of age the thymus contains about 20-fold more cells than wild-type
increased double-negative T cell number ( J:91542 )
• the total number of DN cells is increased 115-fold

endocrine/exocrine glands
thymus hyperplasia ( J:91542 )
• at 4-6 weeks of age the thymus contains about 20-fold more cells than wild-type




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory