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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dapk1tm1Yuk
targeted mutation 1, Kazunori Yukawa
MGI:3052030
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dapk1tm1Yuk/Dapk1tm1Yuk involves: 129P2/OlaHsd * C57BL/6 MGI:3052042


Genotype
MGI:3052042
hm1
Allelic
Composition		 Dapk1tm1Yuk/Dapk1tm1Yuk
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dapk1tm1Yuk mutation (1 available); any Dapk1 mutation (125 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
decreased renal tubule apoptosis ( J:92102 )
• obstructed kidneys from mutant mice display an attenuation of tubular cell apoptosis relative to obstructed wild-type kidneys
• however, no significant difference in interstitial cell apoptosis is noted between obstructed kidneys from wild-type and mutant mice

cellular
decreased renal tubule apoptosis ( J:92102 )
• obstructed kidneys from mutant mice display an attenuation of tubular cell apoptosis relative to obstructed wild-type kidneys
• however, no significant difference in interstitial cell apoptosis is noted between obstructed kidneys from wild-type and mutant mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory