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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gja5tm1(Gja7)Hvr
targeted mutation 1, Harold van Rijen
MGI:3051866
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gja5tm1(Gja7)Hvr/Gja5tm1(Gja7)Hvr involves: 129S2/SvPas * C57BL/6 MGI:3051893
hm2
 		Gja5tm1(Gja7)Hvr/Gja5tm1(Gja7)Hvr involves: 129S2/SvPas * CD-1 MGI:3051892


Genotype
MGI:3051893
hm1
Allelic
Composition		 Gja5tm1(Gja7)Hvr/Gja5tm1(Gja7)Hvr
Genetic
Background		 involves: 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja5tm1(Gja7)Hvr mutation (0 available); any Gja5 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart electrocardiography waveform feature ( J:92018 )
• in an ECG P wave and QRS complex duration are significantly increased suggesting delayed or slower activation of the atria and ventricles




Genotype
MGI:3051892
hm2
Allelic
Composition		 Gja5tm1(Gja7)Hvr/Gja5tm1(Gja7)Hvr
Genetic
Background		 involves: 129S2/SvPas * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja5tm1(Gja7)Hvr mutation (0 available); any Gja5 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal impulse conducting system conduction ( J:92018 )
• the conduction velocity in the left atrium is significantly slower
• activation time of the right ventricle is significantly increased
abnormal heart electrocardiography waveform feature ( J:92018 )
• in an ECG P wave and QRS complex duration are significantly increased suggesting delayed or slower activation of the atria and ventricles




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory