Phenotypes associated with this allele

• Allele Symbol: Mbp^shi-J
• Allele Name: shiverer Jackson
• Allele ID: MGI:3050954
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mbp^shi-J/Mbp^shi-J	BALB/cJ-Mbp^shi-J/GrsrJ	MGI:3697159

Genotype
MGI:3697159

hm1

• Allelic Composition: Mbp^shi-J/Mbp^shi-J
• Genetic Background: BALB/cJ-Mbp^shi-J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal myelin sheath morphology ( J:117543 )

abnormal myelination ( J:117543 )

• lack of central nervous system myelin

behavior/neurological

tremors ( J:117543 )

• general tremor during locomotion visible by 12 days of age

ataxia ( J:117543 )

hearing/vestibular/ear

abnormal auditory brainstem response waveform shape ( J:117543 )

• ABR shows abnormal wave patterns with long interpeak latencies at 2.5 months of age

increased auditory brainstem response wave interpeak latency ( J:117543 )

• at 2.5 months of age

increased or absent threshold for auditory brainstem response ( J:117543 )

• ABR shows 10 to 20 dB elevation of thresholds at 2.5 months of age

vision/eye

vision/eye phenotype ( J:117543 )

N • normal vision by ERG