Phenotypes associated with this allele

• Allele Symbol: Itga6^tm1Son
• Allele Name: targeted mutation 1, Arnoud Sonnenberg
• Allele ID: MGI:3050562
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itga6^tm1Son/Itga6^tm1Son	involves: 129P2/OlaHsd * FVB	MGI:3718224

Genotype
MGI:3718224

hm1

• Allelic Composition: Itga6^tm1Son/Itga6^tm1Son
• Genetic Background: involves: 129P2/OlaHsd * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased T cell number ( J:50235 )

• there is a 30% to 40% reduction in the number of T cells compared to in wild-type mice in peripheral and mesenteric lymph nodes

abnormal T cell physiology ( J:50235 )

• T cell motility is reduced by 46% compared to in wild-type mice on laminin-1

abnormal lymph node morphology ( J:50235 )

• there is a 30% to 40% reduction in the number of T cells compared to in wild-type mice in peripheral and mesenteric lymph nodes

hematopoietic system

decreased T cell number ( J:50235 )

• there is a 30% to 40% reduction in the number of T cells compared to in wild-type mice in peripheral and mesenteric lymph nodes

abnormal T cell physiology ( J:50235 )

• T cell motility is reduced by 46% compared to in wild-type mice on laminin-1