Analysis Tools|
Allele Symbol Allele Name Allele ID |
Slc17a7+ wild type MGI:3049591 |
||||||||||||||||||||
| Summary |
4 genotypes
|
|
|
Data Sources
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• 24 hours following the sample phase, mice do not discriminate the novel object whereas wild-type mice do
|
|
• in a forced-swimming test, mice spend more time immobile compared to wild-type mice
|
|
• mice are more anxious in a light-dark exploration test in that mice spend less time in the white area and crossed fewer lines compared to wild-type mice
|
|
• GABA levels in the frontal cortex and dorsal hippocampus are reduced
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• field EPSP responses increase faster with increased signal strength than for controls
• increased response with increased signal strength fails to reach the level seen for controls
|
|
• reduced LTP as a result of theta burst stimulation
• controls demonstrate a saturated response after the second series while homozygotes continue to show small increases
• maintenance is at a lower level than in controls
|
|
• initial spatial learning ability in a Morris water maze is similar to controls
• slower in relearning platform location when the platform is moved to a different quadrant
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• mice are viable and fertile with no gross physical or behavioral abnormalities
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 10/06/2026 MGI 6.29 |
|
|
|
||
