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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rp1l1+
wild type
MGI:3049469
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Rp1tm1Jnz/Rp1+
Rp1l1tm1Jnz/Rp1l1+ 		involves: 129S7/SvEvBrd MGI:4354113


Genotype
MGI:4354113
cx1
Allelic
Composition		 Rp1tm1Jnz/Rp1+
Rp1l1tm1Jnz/Rp1l1+
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rp1l1tm1Jnz mutation (0 available); any Rp1l1 mutation (78 available)
Rp1tm1Jnz mutation (0 available); any Rp1 mutation (121 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal photoreceptor outer segment morphology ( J:151463 )
• mice at 6 months of age have OS abnormalities similar to Rp1l1tm1Jnz homozygotes
• 16% of mice have swirling discs in the OS compared to under 3% for controls
abnormal rod electrophysiology ( J:151463 )
• the a-wave amplitudes of 6 month old mice are similar to those in Rp1l1tm1Jnz homozygotes (i.e. 70% of normal)
• flash sensitivity of rod photoreceptors is reduced about 50% at 3-4 weeks of age

nervous system
abnormal photoreceptor outer segment morphology ( J:151463 )
• mice at 6 months of age have OS abnormalities similar to Rp1l1tm1Jnz homozygotes
• 16% of mice have swirling discs in the OS compared to under 3% for controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory